Flmodafinil vs Modafinil: What Exactly is the Difference? allmodafinil.com
post-template-default,single,single-post,postid-6465,single-format-standard,bridge-core-1.0.5,ajax_fade,page_not_loaded,,qode-title-hidden,qode_grid_1300,hide_top_bar_on_mobile_header,qode-content-sidebar-responsive,qode-theme-ver-18.1,qode-theme-bridge,qode_header_in_grid,wpb-js-composer js-comp-ver-6.7.0,vc_responsive
Flmodafinil vs Modafinil

Flmodafinil vs Modafinil: What Exactly is the Difference?

Listen to the podcast of this blog :

Flmodafinil vs Modafinil the comparison

Flmodafinil is a new entry to the nootropic list and has been reported by some to be more effective than Modafinil in terms of activation time and fewer side effects. In this article, we shall attempt to determine the extent to which these assertions are correct and also learn the difference between Flmodafinil and Modafinil

What is Flmodafinil?

CRL-40,940 or Flmodafinil is the bisfluoro analog of modafinil. It is a modafinil derivative that lasts 40% longer and has greater bioavailability. That is, it is more easily absorbed and takes less time to take effect although this cannot be verified with proper scientific data and since Flmodafinil was patented in 2013, several clinical trials have been underway. It is found to be a non-amphetamine wakefulness-promoting agent that lasts for longer lengths of time. Since it is under clinical trials for hypersomnia and narcolepsy, it has not acquired any license yet and it is like a research chemical at the moment, the generic versions are being marketed without a prescription as it is not controlled.

Flmodafinil vs Modafinil

To comprehend flmodafinil, one must first comprehend modafinil, its progenitor substance. Modafinil’s processes are not entirely known, but one thing is certain: it functions as a selective dopamine reuptake inhibitor, boosting and extending the activities of dopamine in certain areas of the brain.

This impact is somewhat mild compared to other dopamine reuptake inhibitors, but it is also quite selective. Modafinil, unlike other dopamine reuptake inhibitors, has no effect on the norepinephrine or serotonin systems. However, its dopaminergic effects indirectly raise levels of histamine and orexin, two neurotransmitters that contribute to wakefulness.

As anecdotal reports suggest Flmodafinil works in the same way as its parent drug just that it impacts stronger effects. Even by consuming small quantities, massive effects have been experienced. The chemical raises dopamine levels by binding to D2 receptors. This method of action improves intellect and productivity.

Benefits of Flmodafinil

Flmodafinil’s Potential Benefits Include:

  • Neuroprotective
  • Dopamine Reuptake Inhibitor
  • Antidepressant
  • Anti-aggressive


The drug’s company patented it in 2013, and it has been in phase I clinical studies since 2015.

As of yet, there hasn’t been any strong or persuasive evidence that the medicine is any better than modafinil. But because of similar mechanisms, it will induce alertness and wakefulness just like Modafinil.

Improved motivation, long-lasting energy, and better learning skills are a few more benefits of Modafinil.

Side effects of Flmodafinil

As anecdotal reports suggest it has fewer side effects than Modafinil. A person who takes it may experience the following symptoms:

  • Anxiety
  • Nose congestion
  • Diarrhea
  • Dizziness
  • Sleeping problems
  • Nausea\indigestion
  • Nose congestion and runny nose
  • Blood pressure fluctuation


This supplement may also interact with other supplements. It has the potential to interfere with the action of enzymes in the liver that is responsible for the metabolism of other medications.

When taking flmodafinil or modafinil, alcohol may cause a response. It is important to avoid drinking while using this medication and to always take the specified dosage.

Is Flmodafinil legal?

Modafinil is a schedule 4 drug in the United States, which means it is prohibited to use without a prescription. Most countries treat it in roughly the same way. Armodafinil is included since it is one of the two components of modafinil.

Similarly, Modafinil prodrugs such as flmodafinil, adrafinil, and fladrafinil, are not currently subject to the same restrictions. Each can currently be obtained without a prescription from a variety of websites.

Flmodafinil vs Modafinil

You’re probably aware that Flmodafinil vs Modafinil has a lot in common. However, there are some significant points where they differ, like Flmodafinil is structurally identical to Modafinil, with the addition of two fluoride units. Although their effects are comparable, Flmodafinil is estimated to be stronger than Modafinil and to have a longer half-life (meaning it stays in one’s system for a longer period of time). As anecdotal reports suggest Flmodafinil may have fewer adverse effects than Modafinil, although clinical research data are still pending.

Modafinil is a prescription-only medication while Flmodafinil is not currently available as prescription medicine, however, it is being researched for prospective FDA clearance, so this could change soon. We know a lot more about Modafinil’s safety and effectiveness than we do about Flmodafinil.

In most circumstances, Flmodafinil may be more expensive than Modafinil. It’s more potent and has a fresh formulation.

Why Should You Use Modafinil Instead of Flmodafinil?

Although the concept of enhanced modafinil seems appealing, there is no evidence that Flmodafinil is any better.

Why Should You Use Modafinil Instead of Flmodafinil?

Although the concept of enhanced modafinil seems appealing, there is no evidence that Flmodafinil is any better.

The improved bioavailability has received a lot of attention in internet forums, but despite 30 years since its discovery and three years of phase I clinical testing, nothing has been released by the business that patented it.

Apart from anecdotal reports, there is no research-based evidence of being more potent than Modafinil. Hence we recommend sticking to our known king of nootropics.

No Comments

Post A Comment